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Is Cancer Confined to the Prostate Gland?

These tables may help you and your doctor to predict the chance of organ confined prostate cancer.

Find the table headed with your PSA level. Next, read down the left (orange) column to your Gleason score. Then read across to the column headed by your clinical stage (e.g T2a).
     Where the row for your Gleason meets the column for your clinical stage is a number. This number, e.g. 66, is a percentage - 66%. Your number gives you a rough idea of how many chances out of a hundred a patient with your PSA level, Gleason score and Clinical Stage has of organ confined disease. The higher this number, the better. Remember you're NOT an "average" number!

PSA 0.0 - 4.0 ng/mL

Clinical Stage

 T1a T1b T1c T2a T2b T2c T3a

Gleason Score

Percent probability that prostate cancer is organ-confined

2-4 90 80 89 81 72 77  
5 82 66 81 68 57 62 40
6 78 61 78 64 52 57 35
7   43 63 47 34 38 19
8-10   31 52 36 24 27  

PSA 4.1 - 10.0 ng/mL

Clinical Stage

T1a T1b T1c T2a T2b T2c T3a

Gleason score

Percent probability
2-4 84 70 83 71 61 66 43
5 72 53 71 55 43 49 27
6 67 47 67 51 38 43 23
7 49 29 49 33 22 25 11
8-10 35 18 37 23 14 15 6

PSA 10.1 - 20.0 ng/mL

Clinical Stage

T1a T1b T1c T2a T2b T2c T3a

Gleason score

Percent probability
2-4 76 58 75 60 48 53  
5 61 40 60 43 32 36 18
6   33 55 38 26 31 14
7 33 17 35 22 13 15 6
8-10   9 23 14 7 8 3

PSA above 20.0 ng/mL

Clinical Stage

T1a T1b T1c T2a T2b T2c T3a

Gleason score

Percent probability
2- 4   38 58 41 29    
5   23 40 26 17 19 8
6   17 35 22 13 15 6
7     18 10 5 6 2
8-10   3 10 5 3 3 1

Chart source: Management of Prostate Cancer
ed. Eric Klein, MD, Humana Press, Inc, 2000.

Chart adapted from Sohayda C, Kupelian PA, Klein E.
Extent of extracapsular extension:
implications for planning conformal radiotherapy and brachytherapy.
Int J Radiation Oncol Biol Phys 1998; 42:132

This page compiled by J. Strax April 20, 2006; last modified December 26 2008.

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© 1997-2009 PSA Rising

Online calculators:

For detailed results showing

Probability of Organ Confined Disease, Extraprostatic Extension, Seminal Vesicle Invasion , and Lymph Node Invasion
consult

Partin Tables
at Johns Hopkins Brady Institute

PSA velocity is a key measure of cancer risk.
A PSA velocity calculator is online
at Urological Sciences Research Foundation

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