Resistant Cancers Self-Destruct When Exposed to Experimental Drug
May 3, 2018. PSA Rising / UCSF / San Francisco researchers have discovered a promising new line of attack against lethal, treatment-resistant prostate cancer. Analysis of hundreds of human prostate tumors revealed that the most aggressive cancers depend on a built-in cellular stress response to put a brake on their own hot-wired physiology. Experiments in mice and with human cells showed that blocking this stress response with an experimental drug — previously shown to enhance cognition and restore memory after brain damage in rodents — causes treatment-resistant cancer cells to self-destruct while leaving normal cells unaffected.
The new study was published online May 2, 2018 in Science Translational Medicine. Continue reading “An ‘Achilles Heel’ for Aggressive Prostate Cancer Found, UCSF says”