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Eat to Beat Prostate Cancer Cookbook

Eat to Beat Prostate Cancer Cookbook Author: David Ricketts; buy New: $12.97

Intimacy with Impotence by Ralph Alterowitz

Intimacy with Impotence: The Couple's Guide to Better Sex after Prostate Disease by Ralph Alterowitz, Barbara Alterowitz. Price: $10.20

March 15, 2006

Six Hospitalized in British Drug Trial

category: Cancer posted by admin @ 7:32 pm

By ROBERT BARR Associated Press Writer
© 2006 The Associated Press

LONDON — Two men were hospitalized in critical condition Wednesday and four others were in serious condition after suffering adverse reactions in trials of a new drug, and British regulators ordered the tests suspended.

Parexel International, which supervised the trial, identified the drug as TGN1412, a monoclonal antibody developed by TeGenero AG of Wuerzburg, Germany, for treatment of autoimmune and inflammatory diseases and leukemia.

Ganesh Suntharalingam, clinical director of intensive care at Northwick Park Hospital, said two of the men were in critical condition and four were in serious condition but showing signs of improvement.

“The drug, which is untested and therefore unused by doctors, has caused an inflammatory response which affects some organs of the body,” Suntharalingam said.
(full story…)

Comment (0)
• • •

Hot Peppers - any link with gastric cancer?

category: Prostate Cancer, Nutrition, Cancer posted by admin @ 6:12 am

photo: chili pepper,david allag

Capsaicin, the pungent alkaloid in jalapeños and other chile peppers that makes them hot, drives prostate cancer cells to kill themselves off, according to studies published in the March 15 issue of Cancer Research. See:
http://www.psa-rising.com/eatingwell/peppers_hot.htm

Some commentators reacted by warning that hot peppers may cause gastric cancer. Is this true? How strong is the association?

A study conducted at a Texas Veterans Administration hospital in 1988, published in the JAMA, injected about an ounce of jalapeno pepper directly into the stomachs of volunteers. Follow-up observation showed no damage to their stomach linings. But this did not amount to chronic exposure, and anti-cancer versus cancer-causing effects of capsaicin are still controversial. A couple of years ago Mexico National Institute of Public Health found higher rates of gastric cancer in people who ate the equivalent of 9-25 jalapeno peppers a day compared to people who no more than 3 a day. They found no evidence that bacterioa known to be associated with some types of stomach were causing this increased risk.
(full story…)

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• • •

March 14, 2006

Genistein Reverses Hypermethylation of Genes

category: Prostate Cancer, Nutrition, Cancer posted by admin @ 2:55 pm

Genistein, the major isoflavone from soy, has been shown to have cancer preventive activity, but the mechanisms are not clearly understood. Fang et al. demonstrate that treatment of human esophageal cancer cells with genistein (2–20 mmol/L) caused the reversal of hypermethylation and reactivation of retinoic acid receptor β, p16INK4a, and O6-methylguanine methyltransferase genes. Similar activity is also observed with human prostate cancer cells.

Greater extent of reactivation is observed when genistein is combined with low concentrations of trichostatin, sulforaphane, or 2’-deoxy-5-aza-cytidine. Reversal or prevention of the hypermethylation of key genes by genistein may contribute to its cancer prevention activity.

Source: October 1 Clinical Cancer Research Highlights | American Association for Cancer Research

Note: Sulforaphane is found in cruciferous veggies (brassica) like broccoli, broccoli sprouts, bok choy, kale, collards, cauliflower, cauliflower sprouts, arugula, kohlrabi, mustard, turnip, red radish and watercress, brussel sprouts and cabbage.

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• • •

Taxotere Plus Vaccine

category: Prostate Cancer, Taxotere, Drug Info posted by admin @ 2:30 pm

Docetaxel Plus Vaccine Extends Progression-Free Survival Rates In Prostate Cancer Patients

Docetaxel has activity against androgen-insensitive prostate cancer (AIPC). Arlen et al. designed a randomized Phase II study in AIPC patients to compare a prostate-specific antigen vector–based vaccine vs. vaccine plus docetaxel.

Patients in the vaccine alone arm were allowed to receive docetaxel at progression.

Median progression-free survival rates on docetaxel was 6.1 months after crossover from vaccine vs. 3.7 months with the same drug regimen and patient population in a previous trial. Larger prospective studies will be required to validate these findings.

This was the first study to show that patients in both arms (vaccine ± docetaxel) developed equal T-cell responses to prostate-specific antigen showing that docetaxel (with steroid) did not inhibit immune responses.
source: February 15 Clinical Cancer Research Highlights | American Association for Cancer Research

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• • •

March 13, 2006

Study: Electricity kills cancer cells

category: Prostate Cancer, Cancer posted by admin @ 9:37 pm

High-powered jolts of electricity, repeated many times, kill melanoma cells in mice. Scientists from Old Dominion University and Eastern Virginia Medical School say that using extremely short, high-voltage doses of electricity, they’ve never had a tumor that did not respond to the treatment.
Richard Nuccitelli, associate professor of electrical and computer engineering at Old Dominion, said the method might eventually turn into an effective cancer treatment.
physorg.com

Comment (0)
• • •

February 15, 2006

Avastin costs too much, may kill you too

category: Prostate Cancer, Cancer, Medical Ethics, Avastin posted by admin @ 2:17 am

Today’s New York Times is running a story by Alex Berenson in the business section about Genentech’s Avastin, A Cancer Drug Shows Promise, at a Price That Many Can’t Pay. “Doctors are excited about the prospect of Avastin, ” Berenson writes, “a drug already widely used for colon cancer, as a crucial new treatment for breast and lung cancer, too. But doctors are cringing at the price the maker, Genentech, plans to charge for it: about $100,000 a year.”
(full story…)

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• • •

February 14, 2006

Avastin Trial Deaths

category: Prostate Cancer, Cancer posted by admin @ 10:24 pm

Drug companies stop recruiting for cancer drug test after deaths
PAUL ELIAS
AP via Miami Herald reg Tue Feb 14 200
SAN FRANCISCO - Biotechnology giant Genentech Inc. and its majority stockholder Roche Holding AG said they temporarily halted recruiting volunteers for a large human test of the blockbuster cancer drug Avastin after more patients than expected died.

The deaths occurred among colon cancer patients taking Avastin with a chemotherapy regimen called XELOX. Since the test was started in December 2004, seven patients taking that combination died, four of them suddenly, Roche said in a press release Monday.

“An occurrence of sudden deaths, especially in three younger patients, was noted,” Roche said, adding that the temporary suspension would allow “a full safety assessment.”

Those seven deaths compare to four deaths in another arm of the study that combined Avastin with a different chemotherapy called FOLFOX.

About 2,000 of the 3,450 patients planned for the test already receiving one of three combinations of Avastin and the chemotherapy regimens will continue to receive their drugs. The rest of the volunteers won’t be enrolled for at least 60 days while the companies try to find what caused the deaths.

The test is designed to see if Avastin can safely be used to prevent colon cancer from recurring in patients in remission. The Food and Drug Administration approved Avastin for patients with advanced colon cancer in 2004 and the drug accounted for $1.1 billion in sales for Genentech last year. Basel, Switzerland-based Roche owns sales rights in Europe, where it was approved last year.
Full story online:
http://www.miami.com/mld/miamiherald/13867271.htm

Comment (0)
• • •

BPH Therapy trial suspended

category: Prostate Cancer posted by admin @ 10:10 pm

QLT says therapy fails Phase II trial

Canada’s QLT, a Vancouver-based developer of light-activated pharmaceuticals, says that it is suspending work on an experimental therapy for
enlarged prostate because the drug “did not meet the study’s primary efficacy objective at three months.”

Researchers announced that lemuteporfin failed to significantly decrease
symptoms of benign prostatic hyperplasia after three months of treatment
compared with a placebo.

“While the decrease in AUA (American Urological Association) Symptom Score was consistent with that seen after other minimally invasive therapies there was no significant difference between treatment and sham-control groups.”

“The preliminary result of this trial does not support initiation of Phase
III clinical trials of lemuteporfin in BPH at this time,” commented Bob
Butchofsky, QLT’s acting chief executive officer. “We intend to complete the
analysis of the data, including the six-month measurements, in order to
determine the best path forward.”

source: QLT’s press release, February 14, 2006.

Comment (0)
• • •

February 12, 2006

Aspartame Questioned

category: Nutrition, Cancer posted by admin @ 12:49 pm

The Lowdown on Sweet?
February 12, 2006
By MELANIE WARNER

note — This New York Times article was published today, Feb 12, in the business section, not in the health section. I have edited the links so that you can get hold of Dr. Soffritti’s full text article in .pdf

WHEN Dr. Morando Soffritti, a cancer researcher in Bologna, Italy, saw the results of his team’s seven-year study on aspartame, he knew he was about to be injected into a bitter controversy over this sweetener, one of the most contentiously debated substances ever added to foods and beverages.

Aspartame is sold under the brand names Nutra-Sweet and Equal and is found in such popular products as Diet Coke, Diet Pepsi, Diet Snapple and Sugar Free Kool-Aid. Hundreds of millions of people consume it worldwide. And Dr. Soffritti’s study concluded that aspartame may cause the dreaded “c” word: cancer.

The research found that the sweetener was associated with unusually high rates of lymphomas, leukemias and other cancers in rats that had been given doses of it starting at what would be equivalent to four to five 20-ounce bottles of diet soda a day for a 150-pound person. The study, which involved 1,900 laboratory rats and cost $1 million, was conducted at the European Ramazzini Foundation of Oncology and Environmental Sciences, a nonprofit organization that studies cancer-causing substances; Dr. Soffritti is its scientific director.

The findings, first released last July, prompted a flurry of criticism from the Calorie Control Council, a trade group for makers of artificial sweeteners that has spent the last 25 years trying to quell fears about aspartame. It said Dr. Soffritti’s study flew in the face of four earlier cancer studies that aspartame’s creator, G. D. Searle & Company, had underwritten and used to persuade the Food and Drug Administration to approve it for human consumption. “Aspartame has been safely consumed for more than a quarter of a century and is one of the most thoroughly studied food additives,” read one news release from the council.
(full story…)

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• • •

February 11, 2006

Omega-6 fatty acids hasten growth of prostate cancer cells

category: Prostate Cancer, Nutrition, COX-2 inhibitors, Cancer posted by admin @ 6:50 pm

2006-02-10 10:16:19 -0400 (Reuters Health)

NEW YORK (Reuters Health) - Adding arachidonic acid, an omega-6 fatty acid, to culture media causes prostate cancer cells to grow twice as fast as usual, according to a report in the February 1st issue of Cancer Research.

“Investigating the reasons for this rapid growth, we discovered that the omega-6 was turning on a dozen inflammatory genes that are known to be important in cancer,” lead author Dr. Millie Hughes-Fulford, from the San Francisco VA Medical Center, said in a statement.

Further analysis indicated that arachidonic acid was activating these genes through a PI3-kinase pathway known to play a key role in the pathogenesis of cancer.

Adding an NSAID or a PI3-kinase inhibitor to the culture media blocked the arachidonic acid-induced proliferation of prostate cancer cells, the findings indicate.

In light of the current findings, Dr. Hughes-Fulford said she now avoids cooking with corn oil, which is known to be high in omega-6 fatty acids. “I’m not a physician, and do not tell people how to eat, but I can tell you what I do in my own home. I use only canola oil and olive oil.”

Cancer Research, Feb 1, 2006.
Arachidonic Acid Activates Phosphatidylinositol 3-Kinase Signaling and Induces Gene Expression in Prostate Cancer
Millie Hughes-Fulford1,2,3, Chai-Fei Li, Jim Boonyaratanakornkit and Sina Sayyah
Department of Veterans Affairs Medical Center; Northern California Institute for Research and Education; and University of California, San Francisco, California

News Source: Reuters Health

Comment (1)
• • •

February 10, 2006

Beyond Headlines - diet and cancer

category: Prostate Cancer, Nutrition posted by admin @ 9:48 pm

Responding to news reports of a large US study published in JAMA, which showed that women who began eating a lower-fat diet at over age 50 were not significantly protected from cancer and heart disease, Sarah Keating M.D., a Canadian doctor, wrote to the Toronto Star to say these women’s diets were not strict enough:

The latest study on low-fat diets is further indication that only truly significant changes to our eating habits can reduce our risk of disease.

As a physician, I know that eliminating meat and other animal products from the diet — a step the low-fat dieters in this study did not take — is proven to reduce the risk of heart disease, obesity, and some forms of cancer.

The China Healthy study and other research on populations around the world have already shown that people on plant-based diets have strikingly low cancer rates. This is because vegetarians typically eat less saturated fat, more fibre and are, on average, slimmer than meat eaters. A 2003 study showed that a vegetarian diet lowers serum cholesterol concentrations about as effectively as cholesterol-lowering statin drugs, a key to preventing heart disease.

By choosing a meatless diet rich in naturally low-fat foods, such as beans, whole grains, fruits, and vegetables, we can significantly reduce our intake of artery-clogging saturated fat and protect ourselves from a number of chronic illnesses.

Toronto Star, Letters, Feb 10, 2006

Although headlines claim that the study has shown no benefit for women on the lower-fat diet, comments from some of the researchers themselves indicate that despite the size and cost of this study, the results are far from definitive.

Why? The women switched to a low fat diet relatively late in life. At 8 years out, the study has not run long enough. By today’s standards, the women received inadequate guidance on types of fat to avoid (especially, they were not advised to avoid trans fats). And many of the women on the supposedly “low-fat” diet drifted away from the relatively moderate target levels of fat back to close to a normal US diet. Even so,the women on the low-fat diet actually did develop less cancer. As reported by The Baltimore Sun,

[The study recruited] 48,835 healthy women with an average age of 62 were enrolled. Forty percent of them were given what is descriobed as intensive counseling to help them reduce their fat intake, while the remainder continued with their normal diet.

Even with the counseling, most women were not able to reduce fat consumption from the average of 35 percent of their calories at the beginning of the study to the target of 20 percent.

At the end of the first year, their fat consumption was 24 percent of calories; by the sixth year it had inched back up to 29 percent.

That lower adherence to the diet than planned was, in part, “why we don’t have definitive results yet,” said biostatistician Ross Prentice of the Fred Hutchinson Cancer Research Center in Seattle.

The study did not differentiate between different types of fat.

Prentice cautioned that the subjects were all “very healthy women who were already following most of the [government’s] dietary guidelines,” so their ability to decrease risk by lowering fat might have been low.

“Unhealthy women may gain more benefit.”

The Mercury News presents a Q&A with one of the study leaders, Marcia Stefanick of Women’s Health Initiative:

Best bet: Eat more fruits, veggies

Q What did the Women’s Health Initiative diet study find?

A The study of 48,835 women found that a low-fat diet alone does not prevent breast cancer, colorectal cancer or heart disease in women over 50. However, there were some signs that a low-fat diet might improve health.

Q What were those signs?

A Women who dramatically lowered the amount of fat they ate and increased their consumption of fruits and vegetables had lower rates of breast cancer than women in a comparison group who did not change their diets. Fewer polyps, a potential sign of colon cancer, were found in women who ate a low-fat diet. Women who ate less saturated fat or trans fats and more fruits and vegetables appeared to have a lower risk of cardiovascular disease.

Q Does this mean that I should abandon my low-fat diet?

A Not necessarily. The women in the low-fat group did not reduce their fat intake as much as researchers had hoped. As a result, they say more study of a truly low-fat diet is needed to determine whether it can prevent cancer. More benefits of a low-fat diet may emerge as the women are studied for another five years. In addition, reducing saturated fat and trans fats have been shown to help improve heart health.

Q If a low-fat diet isn’t going to help, what else can I do to prevent heart disease and cancer?

A Researcher Marcia Stefanick of Stanford University recommends following a diet that’s low in saturated and trans fats, and rich in vegetables and fiber, rather than a generic “low-fat'’ diet. Pay attention to total calories and strive to get your weight to a healthy level. Exercise regularly. Women should also get routine mammograms and screenings for colorectal cancer and heart disease risk. Routinely check your cholesterol profile, blood pressure, blood sugar and body weight.

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• • •

Top Abstracts

category: Prostate Cancer posted by admin @ 5:15 pm

What your doctor may be reading according to Doctors Guide listing of top abstracts in prostate cancer for past 14 days:

1. Randomized Phase II study comparing paclitaxel and carboplatin versus mitoxantrone in patients with hormone-refractory prostate cancer. Cabrespine A, et al. Urology. 2006 Feb

2. First- and second-line chemotherapy with docetaxel or mitoxantrone in patients with hormone-refractory prostate cancer: does sequence matter? Michels J, et al.
Department of Medical Oncology, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.

3. Gynecomastia in patients with prostate cancer: update on treatment options.
Autorino R, et al. 1Clinica Urologica, Seconda Universita degli Studi, Napoli, Italy.

4. Insulin Sensitivity During Combined Androgen Blockade for Prostate Cancer.
Smith MR, J Clin Endocrinol Metab. 2006 Jan 24. Massachusetts General Hospital, Boston, MA.
Free Full text in .pdf

5. Prospective comprehensive assessment of sexual function after retropubic non nerve sparing radical prostatectomy for localized prostate cancer. Trinchieri A,et al. Urology Unit Ospedale A. Manzoni Lecco, Italy. Arch Ital Urol Androl. 2005 Dec. “CONCLUSION: Severe erectile dysfunction was observed in most patients after retropubic radical non nerve sparing prostatectomy, but 50% of candidates for radical treatment presents with abnormal erectile function before surgery when appropriately studied. Patients who will recover erectile function could be identified by NPT test before surgery. Depression associated with the fear for intervention is related with erectile dysfunction measured by IIEF scores before surgery, but depression index scores improve after surgery showing that the role of depression in the maintenance of erectile dysfunction is marginal. Sexual counselling and oral treatment facilitate recovery after surgery in patients with optimal erectile function before treatment.”

For 3 month ratings see Doctors Guide Top Abstracts

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• • •

Prostate cancer hormone therapy hard on the heart

category: Prostate Cancer posted by admin @ 11:26 am

Reported by Reuters, Feb 9, We add the abstract from the article, below this report

By Megan Rauscher

NEW YORK (Reuters Health) - Men with recurrent or advanced prostate cancer may be put on hormone therapy to block testosterone production in an effort to halt or slow the growth of the tumor. However, new research shows, this may put them at increased risk for developing insulin resistance and elevated blood sugar levels, which can affect heart health.

These complications of what doctors call androgen-deprivation therapy or ADT may contribute to the high rate of heart disease in men with prostate cancer, Baltimore-based investigators report in the journal Cancer.
(full story…)

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• • •

February 7, 2006

No Miracle Diets for Heart Disease or Cancer

category: Nutrition, Cancer posted by admin @ 4:53 pm

Starting a low-fat diet in mid-life does not, by itself, decrease a woman’s risk of heart disease or stroke or dramatically reduce her risk of breast or colorectal cancer, according to three studies published today of almost 50,000 healthy, post-menopausal women. But don’t break out the ice cream just yet. Once you get into the nitty gritty of the study, the investigators stress, the findings still support the general idea that you need to pay attention to how much fat — and particularly what kinds of fat — you eat.
(full story…)

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• • •

Study Finds Low-Fat Diet Won’t Stop Cancer or Heart Disease

category: Nutrition, Cancer posted by admin @ 4:32 pm

By GINA KOLATA
Published: February 7, 2006

The largest study ever to ask whether a low-fat diet keeps women from getting cancer or heart disease has found that the diet had no effect.

The $415 million federal study involved nearly 49,000 women aged 50 to 79 who were followed for eight years. In the end, those assigned to a low-fat diet had the same rates of breast cancer, colon cancer, and heart attacks and strokes as those who ate whatever they pleased, researchers are reporting today.

Those who ate the higher-fat diets also had no more diabetes, no higher blood glucose or insulin levels, no higher blood pressure. And the different diets did not make much difference in anyone’s weight. By the end of the study, women in the two groups weighed about the same. But women in the low-fat group had slightly lower levels of low density lipoprotein cholesterol, or LDL, which increases heart disease risk.

The results should put an end to more than two decades of speculating that a low-fat diet is protective, said Dr. Michael Thun, who directs epidemiological research for the American Cancer Society. The new study, he said, “was the Rolls Royce of studies that would answer this question.”

Considering the time, effort, and money it takes to do such a study, Dr. Thun and others added, it is unlikely that anything like it will ever be attempted again. “We usually have only one shot at a very large-scale trial on a particular issue,” Dr. Thun said.
Study Finds Low-Fat Diet Won’t Stop Cancer or Heart Disease - New York Times

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• • •

February 2, 2006

category: Nutrition posted by admin @ 9:37 pm

Food firm favors antiobiotic-free poultry,
cage-free eggs, rBST-free milk

Food-service innovator Bon Appetit Management Company has made commitments to purchase cage-free eggs and antibiotic-free turkey and significant amounts of local and regional foods for its 190 cafes in 26 states. Cage-free eggs will be phased in to the sites in the next 12 months, with the eventual goal of having all eggs from uncaged birds.

Bon Appetit, which serves 55 million meals a year, made its move on antibiotic-free turkey meat based on its existing policy for chicken, with the goal of reducing antibiotic use in poultry. All of its cafes served 100 percent locally grown foods from within 150 miles of the serving point on an Eat Local Challenge day last fall.

To secure rBST-free milk in the upper Midwest, the company revived a plant in Bismark, North Dakota, that had been closed for two years. Great Plains Dairy Partners, LLC, took over the dairy and revived its Deja Moo brand, thanks to Bon Appetit’s contract to buy its milk for its regional school and corporate food service accounts.
Bon Appétit Management Co. Pledges to Sell Only Cage-Free Eggs in its Nearly 200 Dining Facilities

This news tip from the news page of Rodale’s The New Farm

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• • •

When it pays to buy organic

category: Nutrition posted by admin @ 9:26 pm

In its February 2006 issue, Consumer Reports magazine outlines the best bargains in organic food. It says new studies show that by eating organic food, “you can greatly reduce your exposure to chemicals found in conventionally produced foods.” The coverage considers the “dirty dozen” crops where USDA figures show the highest levels of pesticide residue as clearly worth the average 50 percent premium.

The magazine says benefits in meat and dairy are clear, but premiums are higher, while buying organic seafood and health care products are not recommended because organic standards are vague. Shoppers are given a list of ways to cut costs, including “go local” and in season at farmers’ markets, join a Community Supported Agriculture (CSA) farm operation and use internet guides for price comparisons.
Full story at Consumer Reports:
When it pays to buy organic

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• • •

January 19, 2006

President Bush To Focus on Health Care Costs

category: Health Insurance posted by admin @ 9:13 pm

Reports indicate that in his State of the Union addres on January 31 Pres. George Bush will focus on cutting healthcare costs. Kaiser Health, in a summary of these news reports, says:

“Bush administration officials have indicated that the president’s Jan. 31 State of the Union address will focus on curbing rising health care costs, among other health care issues, the AP/Long Island Newsday reports.

“Bush officials — ‘echoing hints Bush has provided in recent speeches’ — have outlined the president’s health care agenda to be presented in the address, according to AP/Newsday.”

One trend is toward more privatization:

“Issues include raising the amount allowed to accumulate in existing health savings accounts; offering additional tax breaks for those who purchase private insurance on their own….”

In addition, AP/Newsday reports that Bush will talk about “establishing more portability for health insurance when people change jobs; and providing easier access to information regarding physician pricing and quality. In addition, Bush also will propose increased efforts to adopt electronic medical records, a cap on noneconomic damages in malpractice verdicts and the ability for small businesses to pool the purchasing of health coverage across state lines, AP/Newsday reports.”

Source:
President Bush’s State of the Union Speech To Focus on Strategies for Reducing Health Care Costs - Kaisernetwork.org Jan 19, 2006

Comment (0)
• • •

January 18, 2006

Thalidomide makes comeback as cancer drug and may combine well with heparin

category: Prostate Cancer, Taxotere, Drug Info, Cancer, Thalidomide posted by admin @ 5:48 am

Thalidomide is making a subsidized comeback in Australia to treat multiple myeloma. In the USA thalidomide is already available to treat prostate cancer. It has not been too effective on its own. Giving it in combination with other chemotherapy may increase side effects. But a team of oncologists has found that giving a blood-thinner to prevent clots from thalidomide plus taxane chemotherapy “could provide a therapeutic and survival advantage for patients….”
(full story…)

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• • •

January 17, 2006

“Hot” plant eases bone pain

category: Prostate Cancer, Cancer posted by admin @ 5:05 pm

LAURAN NEERGAARD
Associated Press

WASHINGTON - The dog hopped on three legs, pain from bone cancer so bad that he wouldn’t let his afflicted fourth paw touch the floor. His owner was bracing for euthanasia when scientists offered a novel experiment: They injected a fiery sap from a Moroccan plant into Scooter’s spinal column - and the dog frolicked on all fours again for several months.

The chemical destroyed nerve cells that sensed pain from Scooter’s cancer, not helping the tumor but apparently making him no longer really feel it.

The dramatic effect in dogs has researchers from the National Institutes of Health preparing to test the chemical in people whose pain from advanced cancer is unrelieved by even the strongest narcotics.

The first human study could begin by next year, at the NIH’s Bethesda, Md., hospital. A second study in pain-ridden dogs is slated for this summer at the University of Pennsylvania.
Full story available from these sources:
Plant could hold secret for new pain medication Seattle Times

Sap from `hot’ plant treats pain, Good results on dogs with cancer
Researchers eye future use on humans
Toronto Star, Jan. 17,

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