Russian scientist Anna Prokhorchuck working with UK and US scientists has found that mice lacking a protein called Kaiso show resistance to intestinal cancer. Kaiso, which this study showed is upregulated in intestinal tumors in mice and is expressed in human colon cancers, seems to play “an essential role in mammalian synapse-specific transcription.” they say in a study published this month in Molecular and Cellular Biology.

Mice bred to lack the Kaiso protein were healthy and fertile, with no detectable abnormalities of development or gene expression. “However, when crossed with mice bred to develop intestinal tumors, Kaiso-null mice showed a delayed onset of intestinal tumorigenesis,” the researchers say. “Our data suggest that Kaiso plays a role in intestinal cancer and may therefore represent a potential target for therapeutic intervention.”
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Jan. 13 (Bloomberg) — Cancer patients in the U.K. risk relapses and even death because they do not have enough access to radiation therapy, according to an article published in tomorrow’s issue of the British Medical Journal.

“Radiotherapy services in the U.K. are inferior to those in most developed countries and indeed in many poorer countries,” researcher David Dodwell from the Cookridge Hospital in Leeds wrote in the paper.
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Company stays away from forum
Posted by the Asbury Park Press [New Jersey] on 01/13/06
BY JEAN MIKLE
TOMS RIVER BUREAU

TOMS RIVER — Angered that a representative of Ciba Specialty Chemicals Corp. did not attend the Jan. 9 meeting of the Citizens Action Committee on Childhood Cancer Cluster, Dover Township Council members said Tuesday that they will adopt a resolution demanding that the company send someone to future citizens committee meetings.
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