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PC-SPES Has Estrogen Researchers at the Cancer Institute of New Jersey say that in patients with prostate cancer PC-SPES decreases both PSA and testosterone. While this may account for a problem with blood clots and urges overall caution, it also explains why patients on their own started using PC-SPES. Now research is looking closer, why is the New England Journal of Medicine in a huff?

Bcl-2 Gene Linked to Prostate Cancer in African Americans A gene may play a role in prostate cancer in African Americans. Researchers say this would help explain why black men have the highest rate of prostate cancer in the world.

Combretastatin in Phase I Trials
A drug from the bark of the African bush willow boosts the tumor-cell killing power of radiation up to 500 times, say University of Florida researchers. Trials have begun in Cleveland, Ohio and Middlesex, UK. The drug is expected to work best in combination with radiation and/or chemotherapy.

Proscar (finasteride) Fails to Protect A new study by USC/Norris Cancer Center raises questions about the use of the drug finasteride to prevent prostate cancer. Although small, the study may be significant, researchers say.

"Free" PSA Test May Reduce Need For Some Prostate Biopsies
A new prostate specific antigen (PSA) test that measures the percentage of "free" PSA could spare men a surgical biopsy.

Enhanced Ultrasound for Brachytherapy A new ultrasound imaging technology may reduce the cost and time required to find out if a patient is a candidate for this procedure. The developers say it may also help surgeons place the radioactive seeds more accurately and overcome "Pubic Arch Interference."

Nerve Mapping To Help Keep Sexual Function After Radical Surgery A new surgical tool that can help spare men from becoming impotent after surgery for localized prostate cancer is now being widely tested. The aim is to enhance and improve on existing nerve-sparing surgery.


Viagra by the Numbers Compared with MUSE, Vasomax, and Ginkgo Biloba for Erectile Dysfunction.

Shark Cartilage Fails Clinical Trial Shark cartilage has no activity in patients with advanced cancer and does not help their quality of life, reports Dr. Dennis Miller in the Journal of Clinical Oncology. Miller and his team tested shark cartilage in a Phase I/II clinical trial enrolling 60 patients, 8 with prostate cancer.

AG3340 Anti-angiogenesis Drug in Trials An oral drug for cutting blood supply to tumors is in Phase II/III clinical trials including patients with advanced prostate cancer. Trials of AG3340, a matrix metalloprotease inhibitor, combine it with Novantrone(R) (mitoxantrone) and prednisone.

Painkiller ABT-594 From Frog Poison from the skin of a South American frog has led to a new painkiller more powerful than morphine yet free of morphine's side effects. The new painkiller, ABT-594, has already been tested on animals

Poor Prostate Cancer Care for Black Men; Pain For Hispanics In Texas Studies show cancer care inequalities

Clinical Trials for Older Patients: Medicare Issues, Safety, Fairness One of the stereotypes prostate cancer survivors have to fight is the idea of this as an "old man's disease." Now that elderly cancer patients are at last getting more attention, prostate cancer patients may want to watch this trend.

IGF Crystal Discovery
A team of Australians have discovered the structure of a receptor on the surface of the body cells of all animals including humans. Their description of the outer IGF receptor is likely to increase understanding of diabetes and many forms of cancer including prostate cancer.