Monday, 9 April 2018. By taking a high-cost drug with a low-fat meal—instead of on an empty stomach, as prescribed—prostate cancer patients could decrease their daily dose, prevent digestive issues and cut costs by 75 percent, according to a new study in the March 28, 2018, issue of the Journal of Clinical Oncology (JCO).
Abiraterone acetate, marketed as Zytiga®, is a standard medicine prescribed for metastatic castration-resistant prostate cancer. The pharmaceutical company tells patients on Zytiga to take four of the 250 milligram pills first thing in the morning. Then, having gone without food overnight, they must wait at least one more hour before eating breakfast.
“This schedule is not only inconvenient for patients, it’s also wasteful, in several ways,” said the study’s lead author, Russell Szmulewitz, MD, associate professor of medicine at the University of Chicago and a prostate cancer specialist.