Indications for Prostate Biopsy
| Digital Rectal Exam (DRE) suspicious for cancer at any PSA level |
PSA above 3 ng/mL | High Risk of prostate cancer based on multiple risk factors. |
| TRUS (transrectal ultrasound) Guided Biopsy. In some circumstances, Doppler ultrasound- guided or MRI-guided biopsy may be preferred or required. | If TRUS-guided-biopsy not done, follow up in 6 to 12 months with PSA/DRE. Consider testing FPSA, PHI, and/or PCA3 if PSA is between 3 and 10 ng/mL. | Measure free PSA (FPSA), PHI (Prostate Health Index), or PCA3 in patients with PSA 3 - 10 ng/mL |
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