January 22, 1999. One of the first questions a prostate cancer
patient who is considering surgery should ask his surgeon is, "How
often do you perform this procedure?" That question should be
followed up with, "How often is the procedure performed in this
hospital?"
In a study published in the November 25, 1998
Journal of the American Medical Association, researchers from Memorial
Sloan-Kettering Cancer Center found that mortality rates were 40 to
80% lower in hospitals that had the most experience performing a specific
surgical procedure. The researchers did not zero in on prostate cancer
surgery, but their findings are likely to apply to prostate cancer
as much as to the procedures they examined.
"Surgical management of a patient
with cancer is learned and refined by practice and experience, said
Dr. Murray Brennan, chairman of the Department of Surgery at Memorial
Sloan-Kettering and a co-author of the paper."The more experience
the surgeon has in doing a specific procedure and managing patients
with a specific cancer, the better the patient's chances that he or
she will have a better outcome after the operation."
The researchers looked at outcomes for
cancer patients age 65 years or older at diagnosis by analyzing the
Surveillance, Epidemiology and End Results (SEER) Medicare linked
database from 1984 to 1993. The SEER database registers all cases
of cancer in several defined geographic populations and 97% of all
individuals 65 years of age or older. The researchers chose five of
the most difficult cancer operations including pancreatectomy, esophagectomy,
pneumonectomy, hepatic resection, and pelvic exeneration. The researchers
examined the database to identify a set of patients with the same
type of cancer who were at the same stage of disease and had the same
operation within two months of diagnosis. They then looked at the
30-day mortality rate for each procedure and compared the rates by
hospital volume. In every instance, they found that hospitals with
a high volume of surgery for selected procedures had a substantially
lower surgical mortality rate than hospitals where the surgical team
had limited experience with the procedures.
The results showed similar trends for each
type of surgery. The relationship between outcome and volume was consistently
demonstrated with mortality rates lower in the high volume hospitals.
After 30 days, 12.9% of the patients who had a pancreatectomy performed
in hospitals with a low volume died compared to 7.7% in hospitals
with middle range of volume and 5.8% in a hospitals that had high
volume. The results for esophagectomy were even more striking. The
low volume hospitals had a 30-day mortality rate of 17.3% while the
patient in high volume hospitals had only a 3.4% mortality rate.
"Our study provides evidence in support
of a growing literature that specialist cancer care can significantly
increase a patient's chance of survival," said Dr. Colin Begg,
the study's first author, who is Chairman of the Department of Epidemiology
and Biostatistics at Memorial Sloan-Kettering. "Patients who
are potential candidates for complicated cancer operations should
be made aware of these trends when selecting a hospital."
PSA
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January 22, 1999