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MEDICALPIKE    

Angiogenesis

Tumor Cells Creating Their Own Blood Supply

     
 
Top left: Implanted cancer cells glow with green fluorescence protein.   Top right: Three of the original cancer cells have survived to begin replicating. Signals between the existing blood vessel and the growing cancer cells cause the cells to grow toward the vessel.
   
 
Bottom left: The cancer cells have reached the existing blood vessel.   Bottom right: When they number only 100-300, the cancer cells have created new, fully-functioning blood vessels.
     
Graphic illustration by Stanley Coffman, Duke University Medical Center

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