United States Patent Patent Number: 4424348
Date of Patent: 3 Jan 1984

Methods of manufacture of nitrile-containing glucuronic acid conjugates

Inventor(s): Rubin, David, 5 Rav Zair, Jerusalem, Israel
Assignee: Schwimmer, Adolf W., Savyon, Israel
Schwartz, Irwin Steven, Tel Aviv, Israel
Rubin, David, Jerusalem, Israel
Appl. No.: 78-951270
Filed: 13 Oct 1978


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Art Unit - 123
Primary Examiner - Brown, Johnnie R.
Attorney, Agent or Firm - Browdy and Neimark

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4 Claim(s)

ABSTRACT
Mandelonitrile-.beta.-D-glucuronic acid is produced by condensing a
mandelic amide with a tri-O-acetyl methyl ester of glucuronic acid and
then reacting the product with acetic anhydride to produce the
tri-O-acetyl methyl ester of mandelonitrile-.beta.-D-glucuronic acid.