This does not look as if we PCa patients can expect results as to our disease any time within the next several years.

If phenoxodiol (PXD) is approved for ovarian cancer, a terrible disease, that is fine but will mean little to others.

However: it occurs to me that Proscar and Avodart are approved for tx of BPH, but not for suppression of formation of dihydrotestosterone (DHT). But they are sometimes used “off-label” to do exactly that. I am an example.

So the question occurs: if PXD is approved for ovarian cancer and is thus on the market, might advanced PCa patients see an off-label benefit from its use in their chemotherapy? Hmmm. I hope I don’t have to depend upon this for my survival, but it’s an interesting thought.

Regards,

Steve J

phenoxidiol not only received a fast track designation from the FDA, but yet another designation of which i can’t for the life of me remember the name…

however, it is this secondary designation which will take phenoxidiol directly to market for prostate cancer.

so be patient…i know it’s hard…but, it will happen. just make sure your doctor is familiar with its properties…as i find most doctors are not even aware of its existence.

i am not a doctor, but the wife of a veteran who has a gleason 10 complicated by his exposure to agent orange…he’s managed to keep his numbers down low now for 16 months post radiation…with diet, exercise, and a box full of supplements 4 times a day….the kicker, i believe is fermented soy genistein. he takes over 800 mg. of soy genistein per day…and i buy it from life extension discounted through www.betterlife.com. when he rebelled and stopped taking them his psa climbed and when he resumed, it went right back down. i don’t believe this was a post radiation ”bump” as it’s referred to because he rebels a lot and the psa goes up and down with rebellion and resumption. so, i’m pretty sure that any drug that tweaks genistein may be something to wait for…

in my research, i also found a reference to
FLURBIPROPHEN, TRADE NAME ANSAID…an anti-inflammatory drug. seems a dutch researcher
inadvertently discovered that flurbiprophen interrupts some very necessary signalling pathways for PCa cells. as i accessed clinical trails the other day i noticed there are extensive clinical trials being recruited and conducted on flurbiprophen for PCa. Nothing as innocuous as an aspirin can do any harm for most sufferers (just be careful if you have a sensitive stomach or take blood thinners)so i purchase it from medsmex.com, as the VA will only prescribe proven remedies…not even avodart. i wish i could find a way to order IT online…anything to keep him in good shape until phenoxodiol is approved.

I want to mention that Prof James Morre, who showed that Phenoxodiol slows cancer growth by inhibiting a tNOX pathway (tNOX 75 alpha), has produced a combination of (decaffeinated) green tea and capsicum (hot pepper) which he claims does similarly. For his lab’s finding on tNOX and Phenoxodiol see:
http://www.medicalnewstoday.com/medicalnews.php?newsid=52029

And for Capsol-T, which appears to be available for purchase and might be worth a shot:
http://www.capsol-t.com/howitworks.htm

About hot peppers and PCa:
http://www.psa-rising.com/eatingwell/peppers_hot.htm

Side effects for Flurbiprofen are listed by University of Maryland:
http://www.umm.edu/altmed/ConsDrugs/Flurbiprofencd.html

You also might be interested in these articles:

Vitamin D, NSAIDS provide double whammy against prostate cancer, Stanford study
http://www.psa-rising.com/med/chemo/vitD_NSAIDs05.html

Use of aspirin or other NSAIDs increases survival for men with prostate cancer
http://www.psa-rising.com/med/prevention/NSAIDS_protect1004.htm

An index of our earlier coverage of NSAIDs and PCa:
http://psa-rising.com/med/recurrent/nsaid.htm