June 3, 2015. Radium-223, brand name Xofigo (formerly Alpharadin), is an FDA approved intravenous injectable treatment for painful bone metastases in men with castration-resistant prostate cancer (CRPC). The drug Radium-223 dichloride (radium-223), an alpha emitter, selectively targets bone metastases with alpha particles. Radium-223 is taken by intravenous injection once a month (every four weeks) for up to six months. Radium-223 received priority review two years ago based on its ability to extend Overall Survival as shown in its Phase 3 trial. ...continue reading "Radium-223 linked to longer overall survival in patients with castration-resistant prostate cancer with bone metastases"