June 2, 2015. Primary androgen deprivation therapy for localized prostate cancer increases diabetes risk by up to 60 per cent, particularly in men under 70 years of age, according to research published in the June issue of The Journal of Urology.

"As the benefits of primary androgen deprivation therapy for localized prostate cancer are controversial," the authors say, "and most prostate cancer survivors are of advanced age with comorbidities, it is important to determine if primary androgen deprivation therapy increases the risk of diabetes and to determine the susceptibility factors." ...continue reading "Diabetes A Risk For Men Treated With Androgen Deprivation for Localized Prostate Cancer"

Already available, designed to reduce unneeded biopsies
May 18, 2015 ANN ARBOR, Mich. — A new urine-based test improves prostate cancer detection – including detecting more aggressive forms of prostate cancer – compared to traditional models based on prostate serum antigen, or PSA, levels, a new study finds.

The test, developed at the University of Michigan Comprehensive Cancer Center, is called Mi-Prostate Score, or MiPS. It combines PSA with two markers for prostate cancer, T2:ERG and PCA3, both of which can be detected through a urine sample. The test has been available clinically since September 2013. ...continue reading "Urine-Based Test Improves on PSA for Detecting Prostate Cancer"

May help determine specialized treatment

PSA Rising via TORONTO, Canada – May 27, 2015 – Prostate cancer researchers in Canada have drawn a molecular portrait that provides the first complete picture of localized, multi-focal disease within the prostate and also unveils a new gene subgroup driving it.

...continue reading "Gene Subgroup C-MYC in Aggressive Gleason 7 Prostate Cancer"

Keep walking
Keep Walking
For cancer patients, a brisk walk or a slow jog on a regular basis may be the key to improved cancer treatments.

Brad Behnke, associate professor of exercise physiology at Kansas State University has shown together with colleagues that moderate exercise on a regular basis enhances tumor oxygenation. Getting more oxygen into a tumor may improve treatments in cancer patients. ...continue reading "Moderate Exercise May Make Cancer Treatments More Effective"

In mouse models immune cell manipulation plus chemotherapy achieves prostate cancer remission where chemotherapy alone fails

Blocking or removing immune-suppressing cells , researchers at the University of California, San Diego School of Medicine have found, allows a special type of chemotherapy — and the immune cells it activates — to destroy prostate tumors.

This combination therapy, termed chemoimmunotherapy, achieved near complete remission in mouse models of advanced prostate cancer. ...continue reading "Targeting B Cells to Tackle Immune System Suppression in High Risk Prostate Cancers"

This chart shows the National Cancer Center Network Guidelines, 2014, for use of the PSA test and Digital Rectal Exam (DRE) for early detection of prostate cancer. Recommendations for men over age 70 are below the chart. prostate-cancer-early-detection-chart-png

...continue reading "Prostate Cancer Early Detection Flowchart"

President Obama is proposing "a major new initiative to develop drugs tailored to the genetic characteristics of individual patients, but he expresses deep concern about the costs of such specialty medicines for consumers and for the Medicare program," reports Robert Pear in April 27 New York Times. ...continue reading "Obama Proposes That Medicare Be Given the Right to Negotiate the Cost of Drugs"

Advocating for advanced prostate cancer patients in Scotland, Alister Walker, Chairman and volunteer in Perth & Kinross Prostate Cancer Support Group, writes in the Scottish newspaper The Herald:

"Last week we read the good news that Moderator-Designate of the General Assembly of the Church of Scotland, the Reverend Dr Angus Morrison, has overcome the disease (Church leader in cancer warning , The Herald, April 23). With prostate cancer so often being symptomless in its early stages he is right to urge other men to consider speaking to their GP about the disease. This is particularly important for men aged over 50, black men and men whose father or brother has had the disease - who are at a higher risk. ...continue reading "Abiraterone rejection in Scotland must be overturned, Prostate Cancer advocate says"