Viagra May Shield the Heart from Damage from High Blood Pressure

First evidence that the Impotence Aid Helps a Signaling Protein Protect the Heart

The first direct evidence in lab animals that the erectile dysfunction drug Viagra (sildenafil) amplifies the effects of a heart-protective protein has been reported today by a team of researchers at three leading US medical centers, Johns Hopkins in Baltimore, Tufts Medical Center in Boston and University of North Carolina.

Published in the Journal of Clinical Investigation online, the findings help explain why sildenafil has already been shown to improve heart function and may one day have value in either treating or preventing heart damage due to chronic high blood pressure.

Androgen Blockade for Prostate Cancer May Not Cause Excess Cardiac Deaths

Other adverse effects remain, requiring careful balancing of benefits with risks

Treating prostate cancer patients with drugs that block male hormonal activity does not appear to increase the risk of death from cardiovascular disease, according to a study led by Massachusetts General Hospital (MGH) researchers. But the treatment does increase risks of diabetes and heart disease. How can this outcome hold true?